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PF-04979064
Formula: C11H14N4S
Molecular Weight: 339
110(9):3281-90
ORY-1001 (RG-6016) - LSD1 Inhibitor. CAS# 1431326-61-2 430 PF-04979064ORY 1001, CAS No. 1431326 61 2, is a highly potent and selective inhibitor of Lysine Specific Demethylase 1 (LSD1) with IC50 <20 nM. It is highly selective over related enzymes such as MAO A B. ORY 1001 affects AML stem cells, a sub population of cancer cells that has been proposed to be responsible for frequent relapses of the disease. It significantly reduces tumor cell load and increases survival time in mouse models of Acute Lymphoblastic
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